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Buoyed by a 2-1 win over Genoa, Milan will be aiming to keep their Scudetto hopes alive when they take on Sassuolo in the Serie A round 32.
The Rossoneri are eyeing their third consecutive win in the national championship, and we are positive that they will adopt an attack-minded approach in the midweek clash.
Maldini remains on the sidelines, while Calabria is a major doubt, and he will be assessed ahead of the kick-off. The good news for the hosts is that Zlatan Ibrahimovic returns from suspension.
The Neroverdi, on the other hand, aim to build on back-to-back wins over Benevento and Fiorentina.
Sassuolo, though, have slim chances of booking their place in European competitions, and seeing that Ibra is back for the Rossoneri, home win should be considered.
Ayhan has been tested positive for coronavirus, while Caputo is out of contention through injury for the visiting team.
AC Milan vs Sassuolo Head-to-head
Teams AC Milan Sassuolo played so far 19 matches.
AC Milan won 11 direct matches. Sassuolo won 5 matches. 3 matches ended in a draw. On average in direct matches both teams scored a 3.11 goals per Match.
AC Milan vs Sassuolo Prediction
AC Milan in actual season average scored 2.00 goals per match. In 24 (88.89%) matches played at home was total goals (team and opponent) Over 1.5 goals. In 18 (66.67%) matches in season 2021 played at home was total goals (team and opponent) Over 2.5 goals.
Sassuolo average scored 1.63 goals per match in season 2021. In 14 (87.50%) matches played away was total goals (team and opponent) Over 1.5 goals. In 9 (56.25%) matches played away team was total goals (team and opponent) Over 2.5 goals.
Team News:
Zlatan Ibrahimovic returns to the Milan squad on Wednesday, after serving a suspension last week, so should replace Rafael Leao at centre-forward.
While defender Davide Calabria and young forward Daniel Maldini are set to miss out again for the Rossoneri, coach Stefano Pioli has no other injury concerns, as Alessio Romagnoli returned to the bench last time out.
In Calabria's continued absence, Diogo Dalot will hope to unseat Pierre Kalulu at right-back, with Ismael Bennacer again having to fend off the claims of Sandro Tonali for a role in central midfield.
Though striker Francesco Caputo could still remain sidelined for Sassuolo - along with Kaan Ayhan (COVID-19) and long-term injury victim Filippo Romagna - star man Domenico Berardi returned to spectacular effect at half-time on Saturday and can now start.
Primavera product Giacomo Raspadori should continue up front for the visitors, as Caputo misses out, while Italy international Manuel Locatelli is expected to come back into the XI for Pedro Obiang.
AC Milan possible starting lineup:
Donnarumma; Dalot, Kjaer, Romagnoli, Hernandez; Tonali, Kessie; Castillejo, Calhanoglu, Rebic; Ibrahimovic
Sassuolo possible starting lineup:
Consigli; Muldur, Chiriches, Ferrari, Kyriakopoulos; Lopez, Locatelli; Berardi, Djuricic, Boga; Raspadori